Cyanine5 Boc-hydrazide-Lumiprobe

Cyanine5 Boc-hydrazide

Cyanine5 Boc-hydrazide-Lumiprobe

详细描述

 

订购货号 产品名称及规格 价格(¥)
130A0 Cyanine5 Boc-hydrazide, 1 mg 1430.00
230A0 Cyanine5 Boc-hydrazide, 5 mg 2730.00
430A0 Cyanine5 Boc-hydrazide, 25 mg 5330.00
530A0 Cyanine5 Boc-hydrazide, 50 mg 9035.00
630A0 Cyanine5 Boc-hydrazide, 100 mg 15470.00

 


Boc保护的Cyanine5 hydrazide活性染料用于醛和酮的标记。
Boc- (tert-butoxycarbonyl)保护基团可以通过三氟乙酸或其他强酸去除。活化的hydrazide形成后,便可以进行后续标记羰基基团的反应得到Cyanine5标记的分子。
Cyanine5 Boc-hydrazide-Lumiprobe

相关产品:

Cyanine5 hydrazide, free deprotected hydrazide.


General properties

 

Appearance:

dark blue powder

Molecular weight:

633.26

Molecular formula:

C37H49ClN4O3

Solubility:

good in dichloromethane, polar organic solvents (DMF, DMSO), alcohols, low in water

Quality control:

NMR 1H (95%) and 13C, TLC, functional testing

Storage conditions:

Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light.

Spectral properties

 

Excitation maximum, nm:

646

Extinction coefficient at excitation maximum, Lmol-1cm-1:

250000

Emission maximum, nm:

662

Fluorescence quantum yield:

0.2

 

上海金畔生物科技有限公司

Cyanine7 hydrazide-Lumiprobe

Cyanine7 hydrazide

Cyanine7 hydrazide-Lumiprobe

详细描述

 

货号  描述  人民币价格
15070  Cyanine7 hydrazide, 1 mg  ¥1,430.00
25070  Cyanine7 hydrazide, 5 mg  ¥2,730.00
45070  Cyanine7 hydrazide, 25 mg  ¥5,330.00
55070  Cyanine7 hydrazide, 50 mg  ¥9,035.00
65070  Cyanine7 hydrazide, 100 mg  ¥15,470.00

 


Hydrazide derivative of Cyanine7, a NIR fluorescent dye, an analog of Cy7®.

 

This variety of heptamethine fluorophore contains a six-membered ring rigidizing the polymethine chain which allows to increase quantum yield by 20% compared to parent structure.

 

Hydrazide reacts quickly and smoothly with aldehydes and ketones yielding stable hydrazone products. This reaction is also good for the labeling of glycoproteins after periodate oxidation.

 Cyanine7 hydrazide-Lumiprobe

 

Cy® is a trademark of GE Healthcare.

 

General properties

 

Appearance:

green powder

Mass spec M+ increment:

544.8

Molecular weight:

635.70

Molecular formula:

C37H48Cl2N4O

Solubility:

moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)

Quality control:

NMR 1H, HPLC-MS (95%)

Storage conditions:

Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

 

Excitation maximum, nm:

750

ε, L⋅mol−1⋅cm−1:

199000

Emission maximum, nm:

773

Fluorescence quantum yield:

0.3

 

上海金畔生物科技有限公司

文章号:94-94

Cyanine7.5 hydrazide-Lumiprobe

Cyanine7.5 hydrazide

Cyanine7.5 hydrazide-Lumiprobe

详细描述

 

货号  描述  人民币价格
16070  Cyanine7.5 hydrazide, 1 mg  ¥1,430.00
26070  Cyanine7.5 hydrazide, 5 mg  ¥2,730.00
46070  Cyanine7.5 hydrazide, 25 mg  ¥5,330.00
56070  Cyanine7.5 hydrazide, 50 mg  ¥9,035.00
66070  Cyanine7.5 hydrazide, 100 mg  ¥15,470.00

 


A carbonyl-reactive hydrazide derivative of Cyanine7.5 near infrared (NIR) fluorophore. This dye has similar spectral properties with ICG (indocyanine green), but has a higher quantum yield of fluorescence. Hence, this fluorophore is ideal for in vivo imaging.

 

This is a carbonyl-reactive dye which is particularly useful for the labeling of antibodies after periodate oxidation. It also labels other carbonyl compounds (aldehydes and ketones), for example, many saccharides.

一种羰基活性酰肼衍生的Cyanine7.5近红外荧光团。这种染料和ICG(吲哚菁绿),但是有更高的荧光量子产率。因此,这种荧光团是活体成像的理想选择。

这种羰基活性染料对高碘酸氧化的抗体的标记尤其有效。它也可以用于羰基化合物(醛和酮),比如很多的糖类。

 

Cyanine7.5 hydrazide-Lumiprobe

General properties

 

Appearance:

green powder

Mass spec M+ increment:

644.4

Molecular weight:

735.82

Molecular formula:

C45H52Cl2N4O

Solubility:

moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)

Quality control:

NMR 1H, HPLC-MS (95%)

Storage conditions:

Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

 

Excitation maximum, nm:

788

ε, L⋅mol−1⋅cm−1:

223000

Emission maximum, nm:

808

 

上海金畔生物科技有限公司

文章号:95-95

Cyanine5.5 hydrazide-Lumiprobe

Cyanine5.5 hydrazide

Cyanine5.5 hydrazide-Lumiprobe

详细描述

订购货号 产品名称及规格 价格(¥)
17070 Cyanine5.5 hydrazide, 1 mg 1430.00
27070 Cyanine5.5 hydrazide, 5 mg 2730.00
47070 Cyanine5.5 hydrazide, 25 mg 5330.00
57070 Cyanine5.5 hydrazide, 50 mg 9035.00
67070 Cyanine5.5 hydrazide, 100 mg 15470.00

 


Cy5.5 hydrazide是含羰基的近红外活性染料。酰肼可以与一些羰基化合物迅速反应,例如醛类和酮类,并能形成稳定的腙。该反应可用于标记偶联物的制备。

 

生物分子中的羰基基团可以在氧化应激或蛋白质的脱氨基作用之后自发的形成。或者,醛基可以通过糖蛋白分子糖残基的高碘酸氧化特异生成,例如抗体。抗体可以被高碘酸钠氧化,并且可以被Cy5.5酰肼标记,从而形成Cy5.5酰肼标记的抗体。由于抗体中的糖残基远离可变的表位结合位点,用这种方法标记抗体是很理想的。

 

Cy5.5是一种近红外荧光团,是Cy5®的类似物。它特别适用于对低荧光背景有要求的应用。该染料的吸收和发射波长具有极强的组织穿透力,所以Cy5.5可用于体内近红外成像应用。

Cyanine5.5 hydrazide-Lumiprobe

 

相关产品:

Cyanine3 hydrazide
Cyanine5 hydrazide
Cy® is a trademark of GE Healthcare.


General properties

 

Appearance:

dark blue powder

Molecular weight:

669.73

Molecular formula:

C40H46Cl2N4O

Solubility:

moderate solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)

Quality control:

NMR 1H, HPLC-MS (95%)

Storage conditions:

Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

 

Excitation maximum, nm:

673

Extinction coefficient at excitation maximum, Lmol-1cm-1:

209000

Emission maximum, nm:

707

Fluorescence quantum yield:

0.2

 

 

上海金畔生物科技有限公司

Cyanine5 hydrazide-Lumiprobe

Cyanine5 hydrazide

Cyanine5 hydrazide-Lumiprobe

详细描述

 

订购货号 产品名称及规格 价格(¥)
13070 Cyanine5 hydrazide, 1 mg 1430.00
23070 Cyanine5 hydrazide, 5 mg 2730.00
43070 Cyanine5 hydrazide, 25 mg 5330.00
53070 Cyanine5 hydrazide, 50 mg 9035.00
63070 Cyanine5 hydrazide, 100 mg 15470.00

 


Cyanine5 hydrazide是用于标记醛和酮的活性染料。是Cy5® hydrazide的类似物。
该染料能够很容易与含羰基的分子以近乎理想化的程度反应。比如承受氧化压力的蛋白,糖基化的蛋白通过高碘酸氧化作用重新活化(包括抗体),含醛基的寡核苷酸。
Cyanine5 hydrazide可以替代carbonyl-reactive Cy5®, Alexa Fluor 647, DyLight 649等染料。

 

Cyanine5 hydrazide-Lumiprobe

Cy® is a trademark of GE Healthcare.


General properties

 

Appearance:

dark blue powder

Molecular weight:

569.61

Molecular formula:

C32H42Cl2N4O

Solubility:

significant solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)

Quality control:

NMR 1H (95%) and 13C, TLC, functional testing

Storage conditions:

Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

MSDS:

Download

Spectral properties

 

Excitation maximum, nm:

646

Extinction coefficient at excitation maximum, Lmol-1cm-1:

250000

Emission maximum, nm:

662

Fluorescence quantum yield:

0.2

 

上海金畔生物科技有限公司

Cyanine3 hydrazide-Lumiprobe

Cyanine3 hydrazide

Cyanine3 hydrazide-Lumiprobe

详细描述

 

订购货号 产品名称及规格 价格(¥)
11070 Cyanine3 hydrazide, 1 mg 1430.00
21070 Cyanine3 hydrazide, 5 mg 2730.00
41070 Cyanine3 hydrazide, 25 mg 5330.00
51070 Cyanine3 hydrazide, 50 mg 9035.00
61070 Cyanine3 hydrazide, 100 mg 15470.00

 


Cyanine3 hydrazide属于羰基活性染料,是Cy3® hydrazide的类似物。
该试剂可以用于标记含有羰基的分子比如抗体及其他高碘酸盐氧化反应后的糖蛋白,承受氧化压力的蛋白或去氨基反应的蛋白,还原糖等。Cyanine3可以和很多荧光仪器相兼容。

 

Cyanine3 hydrazide-Lumiprobe
相关产品:

Cyanine5 hydrazide

 

Cy® is a trademark of GE Healthcare.


General properties

 

Appearance:

red powder

Molecular weight:

543.57

Molecular formula:

C30H40Cl2N4O

Solubility:

significant solubility in water, good in polar organic solvents (DMF, DMSO, alcohols)

Quality control:

NMR 1H and HPLC-MS (95%)

Storage conditions:

Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

Spectral properties

 

Excitation maximum, nm:

555

Extinction coefficient at excitation maximum, Lmol-1cm-1:

150000

Emission maximum, nm:

570

Fluorescence quantum yield:

0.31

 

上海金畔生物科技有限公司