TFA-Amino modifier CPG 500-Lumiprobe

TFA-Amino modifier CPG 500

TFA-Amino modifier CPG 500-Lumiprobe

详细描述

订购货号 产品名称及规格 价格(¥)
21860 TFA-Amino modifier CPG 500, 250 mg 1560.00
41860 TFA-Amino modifier CPG 500, 1 g 4940.00
51860 TFA-Amino modifier CPG 500, 5 g 21450.00

This high load, 500 Å controlled pore glass solid support is designed for the synthesis of oligonucleotides containing up to 50 bases with a 3'-amino group. Amino group is protected with trifluoroacetyl (TFA) protection which is easily removed under standard deblock conditions.

The reagent is based on hydroxyprolinol core – a universal non-nucleoside structure that is naturally 100% chiral (no isomers formed upon condensation), and stable to all conditions of oligonucleotide synthesis and deblock.
 


General properties

 

Appearance:

off-white beads

Quality control:

NMR 1H and HPLC (95%) of bound reagent, loading measurement

Storage conditions:

Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Desiccate.

CPG details

 

Pore size, Å:

500

Typical loading, umol/g:

70−90

Coupling conditions:

standard coupling, identical to normal nucleobases

Cleavage conditions:

ammonia, 2 h at room temperature

Deprotection conditions:

identical to protected nucleobases

 

上海金畔生物科技有限公司

文章号:90-90

Alkyne CPG modifier 500-Lumiprobe

Alkyne CPG modifier 500

Alkyne CPG modifier 500-Lumiprobe

详细描述

订购货号 产品名称及规格 价格(¥)
22860 Alkyne CPG modifier 500, 250 mg 1560.00
42860 Alkyne CPG modifier 500, 1 g 4940.00
52860 Alkyne CPG modifier 500, 5 g 21450.00

 


High loading controlled pore glass solid support for the synthesis of oligonucleotides with 3′-alkyne group. With this solid support, synthesis of oligos of up to 50 bases is possible.
Terminal alkyne group can be modified by copper catalyzed Click chemistry (see our recommended protocol for oligonucleotide modification).
This solid support is compatible with standard oligonucleotide deblocking conditions. No special deblocking is required.
 

 

相关产品:

Alkyne Amidite, hydroxyprolinol – alkyne phosphoramidite with DMT group for cartridge and HPLC purification
Alkyne Phosphoramidite, 5′-terminal – solid alkyne phosphoramidite for 5′-terminal modification which is easy to handle and dispense
 

 


General properties

 

Appearance:

off-white beads

Quality control:

NMR 1H and HPLC (95%) of bound reagent, loading measurement

Storage conditions:

Storage: 24 months after receival at -20°C in the dark. Transportation: at room temperature for up to 3 weeks. Avoid prolonged exposure to light. Desiccate.

CPG details

 

Pore size, Å:

500

Typical loading, umol/g:

70−90

Coupling conditions:

standard coupling, identical to normal nucleobases

Cleavage conditions:

ammonia, 2 h at room temperature

Deprotection conditions:

identical to protected nucleobases

 

 

上海金畔生物科技有限公司

文章号:84-84